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Blood pressure drug linked to ethnicity

Posted February 24th, 2015, 02:56 PM IST

Blood pressure drug linked to ethnicity

London: Scientists, led by an Indian-origin researcher are investigating whether treatment for high blood pressure can be improved by taking a person’s ethnic heritage into account.

A wide variety of drugs are available for the treatment of blood pressure and although these are effective and safe, it is often necessary to try different types of drugs and use a combination of two or more drugs.

Delay in choosing the right kind of tablet or combination of tablets through “trial and error” is a major problem and, in a large proportion of people with hypertension, blood pressure is not adequately controlled.

The study, funded by the Medical Research Council and British Heart Foundation, aims to deliver personalised treatment for high blood pressure, based on a single blood test that captures the genetic and other biological factors.

Sandosh Padmanabhan, lead expert, Glasgow University said: “High blood pressure is treated using a range of generic, low cost drugs which are not always effective. We plan to use 21st century high-throughput genomics and metabolomics to explain the mechanism for known differences in drug response observed in different ethnic groups and see if we can use this knowledge to improve hypertension treatment,” said.

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