The ISI of Pakistan has threatened to attack India using a private terrorist organisation in response to the Indian government's decision to repeal article 370.

The head of the ISI gets in touch with a renegade Indian agent named Jim (John Abraham), who plans to exact revenge on India.

Many years ago, when Jim's wife was being held hostage by terrorists, he became bitter toward India because our government did nothing to rescue her.

As part of his plan to create a deadly virus, Jim kidnaps an Indian scientist in Dubai and forces him to work for him. India's top secret agent, Pathaan (Shah Rukh Khan), has been tasked with taking down Jim.

In this case, Pathaan is aided by Rubina, a defected ISI agent (Deepika Padukone). But is he able to rely on Rubina's honesty and integrity?